Understanding the Most Common Side Effects of Myrbetriq: What You Need to Know

Myrbetriq (mirabegron) is a prescription medication approved for the treatment of overactive bladder (OAB) with symptoms such as urgency, frequency, and urinary incontinence. It works by relaxing the bladder muscles, improving the bladder’s ability to store urine, and reducing the symptoms of OAB. Myrbetriq is available in two dosages, Myrbetriq 25 mg and Myrbetriq 50 mg, which are determined by your doctor based on the severity of your condition, medical history, and response to treatment.

While Myrbetriq is effective for many individuals, like any medication, it can cause side effects. Understanding these side effects can help you monitor your response to the medication and address any concerns with your healthcare provider. Below, we will explore the most common side effects of Myrbetriq, along with strategies for managing them.

How Myrbetriq Works

Myrbetriq is classified as a beta-3 adrenergic agonist. This means it stimulates beta-3 adrenergic receptors in the bladder wall, relaxing the detrusor muscle during the storage phase of the bladder cycle. This mechanism increases bladder capacity and reduces the need to urinate frequently or urgently. The two available doses, Myrbetriq 25 mg and Myrbetriq 50 mg, provide flexibility for patients depending on the severity of their symptoms.

Common Side Effects of Myrbetriq

The side effects of Myrbetriq can vary from mild to severe. Below are the most common side effects experienced by patients taking this medication:

1. Increased Blood Pressure

One of the most frequently reported side effects of Myrbetriq is an increase in blood pressure. Clinical trials have shown that some individuals, particularly those taking Myrbetriq 50 mg, may experience elevated blood pressure levels. This occurs because Myrbetriq stimulates beta-adrenergic receptors, which can affect vascular tone.

Symptoms of Increased Blood Pressure:

• Headaches
• Dizziness
• Blurred vision
• Shortness of breath

How to Manage:

• Regularly monitor your blood pressure using a home blood pressure cuff.
• Inform your doctor if you have a history of hypertension before starting Myrbetriq.
• Your healthcare provider may adjust your dosage or recommend alternative treatments if the side effect persists.

2. Urinary Tract Infections (UTIs)

Some patients taking Myrbetriq experience urinary tract infections. This side effect is linked to changes in bladder function, which may occasionally result in incomplete bladder emptying and the growth of bacteria.

Symptoms of a UTI:

• Burning sensation during urination
• Cloudy or strong-smelling urine
• Frequent urination in small amounts
• Lower abdominal pain or pressure

How to Manage:

• Drink plenty of water to flush out bacteria.
• Practice good hygiene to reduce the risk of UTIs.
• Seek prompt medical attention if symptoms of a UTI arise. Antibiotics may be prescribed if an infection occurs.

3. Headache

Headaches are a common side effect of Myrbetriq. They are typically mild to moderate in intensity and may diminish over time as your body adjusts to the medication.

How to Manage:

• Over-the-counter pain relievers like acetaminophen or ibuprofen may help alleviate headaches.
• Stay hydrated and maintain a consistent sleep schedule to reduce headache frequency.
• Consult your doctor if headaches become severe or persistent.

4. Dry Mouth

Dry mouth, or xerostomia, is another frequently reported side effect. This occurs because Myrbetriq can influence the autonomic nervous system, reducing saliva production.

How to Manage:

• Sip water throughout the day to keep your mouth moist.
• Chew sugar-free gum or suck on sugar-free candies to stimulate saliva production.
• Use over-the-counter oral moisturizers if dryness becomes bothersome.

5. Constipation

Some individuals experience constipation while taking Myrbetriq. This side effect may result from the medication’s influence on smooth muscle relaxation, which can slow intestinal motility.

How to Manage:

• Increase your intake of fiber-rich foods like fruits, vegetables, and whole grains.
• Stay hydrated to prevent stool from becoming hard or difficult to pass.
• Engage in regular physical activity to stimulate bowel movements.
• Over-the-counter stool softeners or laxatives can be used under your doctor’s guidance.

6. Fatigue

Fatigue or feeling unusually tired is a common side effect, particularly when starting Myrbetriq. This may be due to your body adjusting to the medication.

How to Manage:

• Get adequate rest and prioritize good sleep hygiene.
• Balance your daily activities to avoid overexertion.
• Speak to your doctor if fatigue persists or interferes with your daily life.

7. Dizziness

Dizziness can occur as a result of changes in blood pressure or the effects of Myrbetriq on the central nervous system.

How to Manage:

• Stand up slowly when transitioning from a seated or lying position.
• Avoid driving or operating machinery if you feel dizzy.
• Let your doctor know if dizziness becomes frequent or severe.

Less Common but Serious Side Effects

Although rare, some individuals taking Myrbetriq may experience serious side effects. It is essential to seek immediate medical attention if you experience any of the following:

1. Allergic Reactions

Severe allergic reactions to Myrbetriq are uncommon but can occur. Symptoms include:

• Rash or hives
• Swelling of the face, lips, or tongue
• Difficulty breathing or swallowing

2. Severe Urinary Retention

In rare cases, Myrbetriq may cause urinary retention, where the bladder does not empty completely. Symptoms include:

• Difficulty starting urination
• A weak urine stream
• A sensation of incomplete bladder emptying

3. Heart Palpitations or Irregular Heartbeat

Some patients may notice changes in their heart rate or rhythm. If you experience chest pain, palpitations, or an irregular heartbeat, consult your doctor immediately.

Comparison of Side Effects: Myrbetriq 25 mg vs. Myrbetriq 50 mg

The risk and severity of side effects can depend on the dosage prescribed. Patients taking Myrbetriq 50 mg are more likely to experience side effects such as increased blood pressure and UTIs compared to those taking Myrbetriq 25 mg. If side effects are bothersome or persistent, your doctor may adjust your dosage or explore alternative treatments.

Who Should Avoid Myrbetriq?

Myrbetriq may not be suitable for everyone. Avoid taking this medication or consult your healthcare provider if you:

• Have severe, uncontrolled hypertension.
• Have a history of allergic reactions to mirabegron or any of its ingredients.
• Are pregnant or breastfeeding (discuss the risks and benefits with your doctor).

Tips for Minimizing Side Effects

• Take as Directed: Follow your doctor’s instructions regarding dosage and timing.
• Communicate with Your Doctor: Report any side effects promptly, especially if they are severe or persist.
• Monitor Your Health: Regularly check your blood pressure, and keep track of any changes in symptoms.
• Stay Informed: Understand the potential side effects of Myrbetriq and discuss any concerns with your healthcare provider.

Conclusion

Myrbetriq is a valuable treatment option for individuals with overactive bladder, offering significant relief from symptoms such as urgency, frequency, and incontinence. However, like any medication, it can cause side effects. The most common side effects include increased blood pressure, UTIs, headaches, dry mouth, constipation, fatigue, and dizziness. While many of these side effects are mild and manageable, it is important to monitor your symptoms and communicate with your doctor to ensure your treatment plan is safe and effective.

If you are considering starting Myrbetriq or have concerns about its side effects, speak with your healthcare provider. They can help determine whether Myrbetriq 25 mg or Myrbetriq 50 mg is the right dosage for you based on your medical history and treatment goals.